SeminarPast EventChronobiology

Why we all need a good night’s sleep

Schedule
Monday, July 12, 2021
15:00 UTC
Amita Sehgal

Dra.

University of Pennsylvania

Host: Brain-Body Interactions

Event Information

Host

Brain-Body Interactions

Duration

70 minutes

Abstract

We seek to determine how circadian rhythms and sleep are integrated with physiological processes to provide optimal fitness and health. Using initially a Drosophila model, and more recently also mammalian models, we have found that aspects of the blood brain barrier (BBB) are controlled by the circadian clock. BBB properties are also influenced by sleep:wake state in Drosophila, and, in fact, appear to be contribute to functions of sleep. This and other work, which implicates sleep in the regulation of metabolic processes, is providing insights into sleep function

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