Topic: ageing

This EMBO Workshop examines how protein synthesis, folding, trafficking, and degradation shape health across the lifespan, connecting fundamental proteostasis mechanisms with ageing and degenerative disease.

International recruitment call for four PhD positions starting between May and September 2027 in Leuven. Projects investigate nervous-system development, ageing, function and disease, including neurodegenerative and neurodevelopmental conditions. The centre combines approaches from molecular and single-cell biology, functional genomics and imaging with AI, neuroengineering and microelectronics. Applicants must select from the advertised projects and identify the relevant supervisor.

Join Marcus Ebeling’s Medical Demography Group to study how medical progress changes disease burden, ageing and population vulnerability. Themes include the distinction between disease presence and impact, diffusion of medical advances, and population resilience. Postdocs contribute to the shared programme while developing an independent research direction, with collaboration across demography, medicine and epidemiology. This vacancy belongs to the September 2026 Max Planck Postdoc Program call, which accepts applications until 13 October 2026 at 12:00 CEST through the official application pla

An audio feature examining research on DNA damage, repair and ageing. The episode explores evidence that inadequate repair contributes to age-related biological changes, and scientific efforts to test whether improving repair can extend healthy life. Nature published this episode on 2 September 2026.

In vision, there is, surprisingly, very little evidence of common factors. Most studies have found only weak correlations between performance in different visual tests; meaning that, a participant performing better in one test is not more likely to perform also better in another test. Likewise in ageing, cross-sectional studies have repeatedly shown that older adults show deteriorated performance in most visual tests compared to young adults. However, within the older population, there is no evidence for a common factor underlying visual abilities. To investigate further the decline of visual

Cerebrovascular support is critical for healthy cognitive ageing. Reduced cerebral blood flow in ageing is caused, among other things, by hypertension, arteriosclerosis (i.e. stiffening of the arteries) and plaque formation. Arterial stiffness is predictive of cognitive decline, is a critical risk factor for cerebrovascular accidents, and has been linked to heightened risks for Alzheimer’s Disease and other forms of dementia. The elasticity of cerebral arteries is influenced by lifestyle factors, including cardiorespiratory fitness. Monica will discuss data obtained in their laboratory with ne

Our ability to perceive the world around us can be affected by a number of factors including the nature of the external information, prior experience of the environment, and the integrity of the underlying perceptual system. A particular challenge for the brain is to maintain a coherent perception from information encoded by the peripheral sensory organs whose function is affected by typical, developmental changes across the lifespan. Yet, how the brain adapts to the maturation of the senses, as well as experiential changes in the multisensory environment, is poorly understood. Over the past f

Hilde Loge Nilsen discusses research on ageing, cellular repair and proposals to extend healthy life. Conversation in Norwegian.

Age-associated dementias are neuropathologically characterized by the identification of hallmark intracellular and extracellular deposition of proteins, i.e., hyperphosphorylated-tau, amyloid-β, and α-synuclein, or cerebrovascular lesions. The neuropathological assessment and staging of these pathologies allows for a diagnosis of a distinct disease, e.g., amyloid-β plaques and hyperphosphorylated tau pathology in Alzheimer's disease. Neuropathological assessment in large scale cohorts, such as the UK’s Brains for Dementia Research (BDR) programme, has made it increasingly clear that the ageing

Reducing protein intake (and that of key amino acids) extends lifespan, especially during mid-life and early late-life. Yet, due to a powerful protein appetite, reducing protein in the diet leads to increased food intake, promoting obesity – which shortens lifespan. That is the protein paradox. In the talk I will bring together pieces of the jigsaw, including: specific nutrient appetites, protein leverage, macronutrient interactions on appetite and ageing, the role of branched-chain amino acids and FGF-21, and then I will conclude by showing how these pieces fit together and play out in the mo