Synthetic Biology podcasts

Sean Carroll talks with Caltech researcher Erik Winfree about programming DNA to process information and build microscopic machines. They discuss molecular computation, self-assembly, biological information processing and the prospects for DNA-based robots in biology and medicine.

Hosted by Sean Carroll

Vincent Racaniello, Kathy Spindler and Brianne Barker discuss research using generative AI to design complete bacteriophage genomes, including reported viable phages active against antibiotic-resistant bacteria. They also examine a study linking recombinant shingles vaccination with lower cardiovascular-event risk. The discussion connects genome modelling, experimental virology and vaccine research, alongside listener letters and weekly selections.

Hosted by Vincent Racaniello, Brianne Barker

The concluding episode of Unexplainable’s Life from Scratch series asks how researchers should judge risks when attempting to redesign living systems. Kate Adamala, David Relman and John Glass discuss synthetic biology and concerns about mirror life, whose molecular handedness would differ from that of existing organisms. The conversation considers the limits of anticipating biological consequences, the responsibilities of researchers and reasons to pause particular lines of work.

Nature's podcast explores genetically engineered probiotic bacteria that sense elevated glucose and release therapeutic factors, lowering blood sugar in animal studies. The episode also covers ecological research on pumas, geological erosion, and how a solar eclipse can help researchers probe the Sun's magnetic corona.

Nature journalists discuss a chemical route that converts PVC waste into motor lubricant and engineered yeast that produces a potential cancer drug.