Topic: action choice

Dorsolateral prefrontal cortex (DLPFC) and dorsal premotor cortex (PMd) are two association brain areas implicated in decision making. However, whether these brain areas have similar or distinct decision-related dynamics remains an open question. In addition, anatomical studies suggest considerable connectivity heterogeneity between DLPFC areas and parietal lobe, temporal lobe, and ventrolateral prefrontal cortex. Whether different areas within the DLPFC also demonstrate distinct decision-related dynamics is also an open question. We addressed these open questions by comparing the neural dynam

Perceptual decision-making involves combining sensory evidence with available choices to arrive at an appropriate action to report the choice. When sensory evidence and potential actions to report choice are simultaneously available, neural activity in dorsal premotor (PMd) and lateral intraparietal (LIP) cortices covary with sensory evidence and choice. However, when sensory evidence and possible actions are separated in time, PMd and LIP show action selection related responses and only when the stimulus-response relationship is apparent. Thus, these areas are largely involved in action selec