Developmental experience of scarcity affects adult responses to negative outcomes and uncertainty
Wan Chen Lin,Christine Liu,Polina Kosillo,Lung-Hao Tai,Ezequiel Galarce,Helen Bateup,Stephan Lammel,Linda Wilbrecht · COSYNE 2022
Understanding the effects of scarcity and uncertainty on the developing brain and behavior has been a major challenge for neuroscience and evolutionary biology. Currently, over millions of households with children and adolescents worldwide experience insecure and uncertain access to food, a.k.a. food insecurity. The goal of our work is to investigate if transient food insecurity experience during the juvenile-adolescent developmental period has lasting effects in adult learning, decision making, and dopamine system in a mouse model. We manipulated feeding schedules from postnatal day(P)21 to 4
Fri, Mar 18, 2022