Topic: aerobic exercise

Aims: Converging evidence indicates beneficial effects of aerobic exercise on motor learning performance. Underlying mechanisms might be an impact of aerobic exercise on neuroplasticity and cortical excitability. Evidence suggests that motor learning and cortical excitability alterations correlate with the intensity of aerobic exercise and the activity level of participants. Thus, this study aims to investigate the effects of different aerobic exercise intensities on motor learning and cortical excitability in healthy individuals. Methods: The study was conducted in a cross-over and double-bli

Cognitive impairments associated with schizophrenia (CIAS) are modelled in rodents using sub-chronic administration of phencyclidine (scPCP). Changes to inflammatory markers have been associated with CIAS in patients, while exercise can improve cognition clinically and pre-clinically. This study aimed to investigate the effect of exercise on cognition and inflammation in the scPCP mouse.Adult female c57 mice were dosed with vehicle (0.9% saline, n=28) or PCP (10mg/kg, n=28) once daily for 10 days and divided into sedentary or exercised groups. Exercised mice had running-wheel access for 1h dai