The protective role of Alchornea laxiflora (Benth.) Pax & K. Hoffman extract against lead-induced neurodegeneration in cockerel chickens
Olumayowa Igado, Oluwaseun Esan, Omowumi Femi-Akinlosotu, Ademola Oyagbemi, Temidayo Omobowale, Omolade Oladele, Evaristus Nwulia · FENS Forum 2024
Lead (Pb), a ubiquitous, non-biodegradable heavy metal contaminant, has significant impact on human and animal health. The adverse effect of lead on avian health and productivity has received little attention, considering the fact that they are sentinels. Alchornea laxiflora (Benth), family Euphorbiaceae, grows naturally in the Nigerian rain forest. Decoction of the leaves is administered traditionally to treat inflammatory and infectious diseases. Ethanol extract of Alchornea laxiflora (EaAL) leaves was used in this study to ameliorate lead-induced neurodegeneration. Five-week-old cockerels,