Topic: Allen Institute Visual Behavior 2p Dataset

VIP inhibitory neurons in the cortex receive neuromodulatory and top-down feedback inputs, hence they are well-suited to process behavioral and predictive signals. A recent study found that VIP neurons respond to unexpected image omissions in an image sequence (Garrett et al., 2020). This omission-evoked activity may represent changes in the animal’s behavioral state (e.g., running or arousal), or it may represent a prediction-error signal that could either be stimulus specific, as suggested by the classical predictive coding models (Rao & Ballard, 1992), or stimulus non-specific. We investiga