Topic: ambiguous stimulus

During hunger onset, animals need to reprioritize the behaviours they express to maximize the chance of finding food. Selecting the appropriate actions requires them to gauge their internal hunger-state but also to weigh up the value of inputs coming from their external environment. The neural mechanisms that underlie this survival-linked perceptual decision-making are of significant interest, but poorly understood.To identify the underlying neural mechanisms of these motivational state dependent decisions, we used the mollusc, Lymnaea stagnalis, whose behaviours have been extensively characte

The perception of an ambiguous stimulus rely on the activation of multiple cortical areas, operating a sensorimotor transformation along the cortical hierarchy. Furthermore, choice related information is found as upstream as the primary sensory areas, suggesting bi-directional communication at all stages of the cortical hierarchy. How do sensory and choice related activities flow and organize across multiple brain areas? Here, we designed a two-alternative forced-choice task (2AFC) in which mice compared stimulation frequencies applied to two adjacent vibrissae. Using two-photon functional ima