Topic: antimicrobial resistance

Laboratory-evolved gentamicin-resistant bacteria are analysed using whole-genome sequencing and protein-structure modelling. The study focuses on mutations in elongation factor G and compares AlphaFold2 predictions with wild-type proteins. Aligning predicted EF-G structures with experimental ribosome and antibiotic-bound structures reveals how local conformational and physicochemical changes could affect drug binding. The talk examines subtle structural shifts, mutations without detectable structural changes, and the limitations of prediction alone. It presents a workflow that combines genomic

Examine how African laboratory systems can translate diagnostic innovation into accessible and resilient health services. The programme links country implementation experience with research on antimicrobial resistance, outbreak genomics and integrated diagnostics. Sessions evaluate financing, workforce development, regional manufacturing and procurement, AI-enabled testing and environmentally sustainable laboratory operations. Debates and panels examine how evidence can guide the transition from short-term emergency capacity to durable national systems. 8–11 December. Daily activities begin a

The hosts discuss nitrogen fixation in a marine alga and the evidence for a nitrogen-fixing organelle. Related topics include plastic pollution, antimicrobial resistance and the rumen microbiome. The episode links microbial evolution and physiology with marine nutrient cycling.