The true cost of air pollution on neurodevelopmental disorders: Postnatal PM10 exposure impairs normal development in transgenic ApoE mice
Rocío Rodulfo Cárdenas, Judit Biosca-Brull, Séfora Barberà-Parada, Diego Ruiz-Sobremazas, Jordi Blanco, Maria Cabré, Fernando Sánchez-Santed, Caridad López-Granero, Maria Teresa Colomina · FENS Forum 2024
Evidences linking air pollution and neurodevelopmental disorders are gaining a great support on the last years. Specifically, traffic-related air pollution (TRAP) has proven to negatively affect cognitive and behavioral development in children. Among different types of air pollutants, particulate matter (PM) is the one most linked with these adverse consequences. On the other hand, APOE is a polymorphic human gene that has three different alleles (e2, e3, e4), being the e3 the most prevalent allele in general population. Moreover, the e4 allele has been associated with increased risk of Alzhei
ePoster · Neuroscience