Topic: associative striatum

Hallucinations are percepts experienced in the absence of external sensory input. Patients with hallucinations show both behavioral and neural alterations in statistical learning in simple sensory tasks. Predictive processing accounts of hallucinations suggest that these alterations bias patients’ perception toward their sensory expectations. However, 1) whether this framework holds when considering real-world hallucinations with complex content and 2) which upstream neural mechanisms cause these alterations in learning are hotly debated. To address these questions, we used fMRI to record neur

Decision-making can be defined as cognitive process based on the selection of a goal-directed action from a set of choices. In perceptual decision-making, this behavior guiding choice relies on sensory information. The associative part of the striatum has been proposed to be essential for such decision-making processes, in particular to select the appropriate action plan according to the sensory evidence. Parvalbumin interneurons (PVI) in the associative striatum may have a crucial role in this action plan selection despite their low numbers. Indeed, by inhibiting striatal processing, PVI may