Topic: aversive learning

We never stop learning when we suffer, but we all learn in unique ways. Adaptive learning helps us cope with adversities, whereas maladaptive learning could hinder coping and lead to more suffering. Indeed, maladaptive aversive learning is thought to be associated with both mental health disorders and chronic pain. However, we currently lack tools to quantify aversive learning at scale. We have developed a suite of game-like cognitive tests which helps us tease apart individual differences in aversive learning, which can be performed by anyone, in the comfort of their home, using a touch based

The hippocampus and the amygdala are two structures required for emotional memory. While the hippocampus encodes the contextual part of the memory, the amygdala processes its emotional valence. During Non-REM sleep, the hippocampus displays high frequency oscillations called “ripples”. Our early work shows that the suppression of ripples during sleep impairs performance on a spatial task, underlying their crucial role in memory consolidation. We more recently showed that the joint amygdala-hippocampus activity linked to aversive learning is reinstated during the following Non-REM sleep epochs,