Responses to inconsistent stimuli in pyramidal neurons: An open science dataset
Colleen J. Gillon, Jérôme A. Lecoq, Jason E. Pina, Timothy M. Henley, Yazan N. Billeh, Shiella Caldejon, Jed Perkins, Matthew T. Valley, Ali Williford, Yoshua Bengio, Timothy Lillicrap, Joel Zylberberg, Blake A. Richards · COSYNE 2023
Sat, Mar 11, 2023
Pyramidal neurons have apical dendrites that are both physically and electrically segregated from their cell bodies. In sensory cortex, these apical dendrites receive primarily top-down signals from associative and motor regions, while the cell bodies and nearby dendrites of these same pyramidal neurons are mostly targeted by bottom-up or locally recurrent inputs from the sensory periphery. Due to these differences, a number of theories in computational neuroscience postulate a unique role for apical dendrites in shaping sensory processing and plasticity in the face of new or surprising stimul