Direct cortical inputs to hippocampal area CA1 transmit complementary signals for goal-directed navigation
John Bowler & Attila Losonczy · COSYNE 2023
The entorhinal cortex (EC) is central to the brain’s navigation system. Its subregions are conventionally thought to compute dichotomous representations for spatial processing: medial entorhinal cortex (MEC) provides a global spatial map, while lateral entorhinal cortex (LEC) encodes specific sensory details of experience. While local recordings of EC circuits have amassed a vast catalogue of specialized cell types that could support navigation computations in the brain, we have little direct evidence for how these signals are actually transmitted outside of the EC to its primary downstream re
Sun, Mar 12, 2023