Comparing stimulation and lesioning in a network model of essential tremor: Mechanisms and treatment
Nada Yousif, Roman Borisyuk, Ayesha Jameel, Joely Smith, Wladyslaw Gedroyc, Brynmor Jones, Dipankar Nandi, Peter Bain · FENS Forum 2024
Essential tremor (ET) is characterised by oscillations of the upper limb, impacting severely on daily activities. Treatments include deep brain stimulation (DBS) and MR guided focussed ultrasound (MRgFUS). In DBS, electrodes are implanted into the ventral intermediate nucleus (VIM) of the thalamus. and a current is applied. MRgFUS non-invasively creates a lesion in the VIM using ultrasound. Both DBS and MRgFUS have been proposed to target the dentatorubrothalamic tract (DRTT) which connects the dentate nucleus with the thalamus and motor cortex, and particularly the posterior part. Recent work
ePoster · Neuroscience