ePoster · Computational Neuroscience
Physiological Implementation of Synaptic Plasticity at Behavioral Timescales Supports Computational Properties of Place Cell Formation
Hsuan-Pei Huang, Han-Ying Wang, Ching-Tsuey Chen, Ching-Lung Hsu · Bernstein Conference 2024
Creating place fields in place cells is crucial for forming spatially dependent episodic memories in the brain, with the hippocampus playing a central role. Specifically, we focus on CA1 pyramidal neurons, which receive inputs from the CA3 and entorhinal cortex (EC). No widely accepted network-based theory for place field formation exists, but many models offer mechanisms for place-field firing. One type of hypotheses proposes that it results from summated output of spatially tuned cells, like grid cells or boundary vector cells. Another suggests CA1 place fields are replicate of CA3 place fie