Topic: behavioural adaptation

The prefrontal cortex is involved in cognitive flexibility. Independently of the task, individual and concerted neuronal activity is related to behaviour, task episodes, and prediction of future choices. However, not every choice arises from the same motivation. Choices can be spontaneous, based on information from previous experience, or querying for additional information. What are the neuronal dynamics governing these possibilities? We simultaneously record hundreds of individual neurons from the mouse prefrontal cortex using silicon probes. Head-fixed animals engage in a probabilistic 2-si

The ability to detect, represent and exploit statistical regularities in the environment is a key feature of animal cognition. The brain holds internal models of the world to optimally interpret incoming sensory inputs and guide the appropriate responses. Previously, we have shown that humans and rodents are sensitive to the underlying sensory statistics in a 2-alternative-forced-choice auditory categorisation task. In this work, we investigate the neural signatures of behavioural adaptation to changes in sensory statistics, where the sampling distribution of sounds within each category is mod