Topic: bone

Neil Shubin investigates the origins of vertebrate teeth and bone through fossils, comparative anatomy and modern imaging. Evidence from early jawless fishes places related tissues in external armour and suggests an initial sensory role for tooth-like structures. The lecture also considers the early appearance of tissue remodelling and other familiar skeletal properties.

Work in my laboratory is based on the assumptions that we do not know yet how all physiological functions are regulated and that mouse genetics by allowing to identify novel inter-organ communications is the most efficient ways to identify novel regulation of physiological functions. We test these two contention through the study of bone which is the organ my lab has studied since its inception. Based on precise cell biological and clinical reasons that will be presented during the seminar we hypothesized that bone should be a regulator of energy metabolism and reproduction and identified a bo