Topic: calcium fluorescence

The stability of the relationship between neural activity and external variables is a matter of debate for many brain areas [1-5]. Whether neural representations are stable or "drifting" has significant implications for how downstream neural populations process these representations and incorporate them into computations driving perception, behavior, and memory. Most studies on the stability of neural coding for movements have focused on simple, stereotyped, and overtrained behaviors, finding that neural representations are stable [6-8]. However, it is unclear if this stability results from t

We present a comprehensive dataset of neural activity, compiled from 11 neuroimaging experiments in the nematode worm C. elegans. These source datasets, while collected under different experimental protocols, all measure neural activity via changes in calcium fluorescence in labeled subsets of the hermaphrodite worm’s 300 neurons. Our contribution is to standardize these disparate datasets into a unified framework including ordering the neural data from labeled neurons consistently, resampling traces to a common timestep, and including a feature mask to indicate which neurons were labeled in e