Seminar · Behavioral Neuroscience
Astrocytes encode complex behaviorally relevant information
Katharina Merten · Nimmerjahn Lab, Salk Institute
Wed, Jan 26, 2022 · 17:35 UTC
While it is generally accepted that neurons control complex behavior and brain computation, the role of non-neuronal cells in this context remains unclear. Astrocytes, glial cells of the central nervous system, exhibit complex forms of chemical excitation, most prominently calcium transients, evoked by local and projection neuron activity. In this talk, I will provide mechanistic links between astrocytes’ spatiotemporally complex activity patterns, neuronal molecular signaling, and behavior. Using a visual detection task, in vivo calcium imaging, robust statistical analyses, and machine learni