Topic: central nucleus of the amygdala

Emotions play an adaptive role in shaping neural representations of strong aversive memories. Complex mood disorders like post-traumatic stress disorder (PTSD), depression and anxiety share common symptoms of memory impairment, though their link to mechanisms of memory consolidation is not well understood. The strength of ensemble formation in micro- and macro-circuits between the central nucleus of the amygdala (cea) and the hypothalamic paraventricular nucleus (pvn) facilitates associations between different internal states, innate behaviour and aversive experiences. Understanding how ensemb

Propionic acid (PA), a short-chain fatty acid and a metabolite of the gut microbiome, plays a significant role in health but has been associated with various pathologies, including autism spectrum disorder (ASD). Experimental studies in rodents have shown that elevated levels of PA can induce molecular and immune changes similar to those observed in ASD (MacFabe, et al.). However, limited knowledge exists regarding its impact on brain structural integrity. In this study, we examined the effects of a single intraperitoneal injection of PA at a dose of 175 mg/kg on adolescent male Wistar rats. S