Topic: clinical translation

Support for early independent neuroscientists addressing significant questions about the brain, including basic research with potential clinical translation. Up to ten awards provide USD 225,000 over three years from 1 June 2027, paid as USD 75,000 annually. Research expenses are supported; indirect costs are excluded. Applications are due 3 November 2026 at 17:00 Central time; reference letters are due 24 November. The application includes a research proposal, diversity and inclusion statement, CV, other-support information, publication links and three references.

This investigators workshop examines adeno-associated virus gene therapies for epilepsy from design and animal testing through clinical translation. Research examples concern Lafora disease, SCN1B-related Dravet syndrome and SLC6A1-related neurodevelopmental disorder. The panel considers treatment efficacy, seizure-associated adverse effects and AAV toxicity, alongside strategies for overcoming current limitations. Discussion also covers biomarkers, scalability and the evidence needed to advance candidates beyond preclinical studies. Sunday 6 December, 14:00–15:30 Mountain Standard Time (Amer

A Keystone Symposium bringing together single-cell genomics, spatial biology, perturbation technologies, computational methods, and clinical translation across high-burden diseases.

Develop non-invasive neurotechnology based on focused ultrasound and targeted drug delivery. Projects may combine hardware and software, MRI-guided targeting, electrophysiology, closed-loop neuromodulation and preclinical experiments, with collaboration on clinical translation.