Dorsal and median raphe neuronal firing dynamics characterized by non-linear measures
Claudia Pascovich, Diego Serantes, Alejo Rodriguez, Diego Mateos, Joaquín González, Diego Gallo, Mayda Rivas, Andrea Devera, Patricia Lagos, Nicolás Rubido, Pablo Torterolo · FENS Forum 2024
The dorsal (DRN) and median (MRN) raphe are important nuclei implicated in sleep and mood regulation. The DRN is mainly serotonergic, where neurons have regular spiking activity, slow firing rate (FR), and long action potential duration (APD). The MRN has more diverse neurochemical and electrophysiological features. In the present study, we aimed to enrich the characterization of the raphe nuclei neurons by using non-linear measures. This was done by analysing the neuronal basal firing profile in both nuclei of urethane-anesthetized rats using Ordinal Patterns (OP) Entropy, Bins Entropy, and P
ePoster · Neuroscience