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Combinatorial threshold linear network

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Networks of interconnected neurons display diverse patterns of activity. Relating these patterns to the structure of the network is a central goal of theoretical neuroscience. Classic neural field and rate models have been powerful tools for this purpose due to their analytical tractability. Here, we show that the recently-developed combinatorial threshold-linear network (CTLN) model is a mean-field theory for excitatory-inhibitory Hawkes networks, with clustered connectivity, in an inhibition-stabilized regime. This mapping allows us to leverage powerful analytical results for CTLN networks

Wed, May 13, 2026 · 15:00 UTC

Seminar · Computational Neuroscience

Dynamics of clustered spiking networks via the CTLN model

Caitlin Lienkaemper, Gabriel Ocker · COSYNE 2025

Networks of interconnected neurons display diverse patterns of collective spiking activity. Relating this collective activity to the network's connectivity structure is a key goal of computational neuroscience. We approach this question for clustered networks, which can form via biologically realistic learning rules and allow for the re-activation of previously evoked patterns. Previous studies of clustered networks have focused on metastabilty between fixed points corresponding to individual clusters, leaving open the question of whether clustered spiking networks can display more rich dyna

ePoster · Computational Neuroscience