ePoster · Computational Neuroscience
Top-down modulation shapes timescales via synaptic plasticity in cortical circuits with multiple interneuron types
Fabio Veneto, Marcel Jüngling, Leonidas Richter, Luca Mazzucato, Julijana Gjorgjieva · Bernstein Conference 2024
Neural activity in the cortex exhibits a wide range of timescales, allowing animals to respond to rapidly changing sensory stimuli while maintaining information in working memory. The timescales of neural activity are not only affected by bottom-up sensory inputs, but also by top-down inputs originating from corticocortical and neuromodulatory pathways. In addition, cortical circuits comprise a large diversity of cell types connected in non-random ways, which are the subject of profound plasticity dynamics. Due to this complexity, understanding how top-down projections affect the timescales of