Topic: cross-validation

A one-year machine-learning research internship with the Allen Institute Neural Dynamics accelerator. The intern will analyze recordings from two genetically distinct neural populations in the striatum alongside motor output, muscle activity and behavioral video. The project asks how shared and population-specific neural activity encodes movement, using latent-variable models, regression, classification and cross-validation. Work includes reproducible Python analysis and communicating results through figures and methods that may contribute to a poster or publication. No previous neuroscience b

Restoring hand function is a top priority for individuals with tetraplegia. This challenge motivates considerable research on brain-computer interfaces (BCIs), which bypass damaged neural pathways to control paralyzed or prosthetic limbs. Here, we demonstrate the BCI control of a prosthetic hand using intracortical recordings from the posterior parietal cortex (PPC). As part of an ongoing clinical trial, two participants with cervical spinal cord injury were each implanted with a 96-channel array in the left PPC. Across four sessions each, we recorded neural activity while they attempted to pr