Topic: DBSCAN

Neuronal ensembles, groups of simultaneously active neurons, are considered to be one of basic forms of information representation in the mammalian cortex. However, the mechanisms underlying the modulation of neuronal ensembles yet remain to be fully understood. Here, we investigated external input-dependent modulation of neuronal ensembles in cultured neuronal networks with modular connectivity mimicking the mammalian cortex. The modular neuronal networks were fabricated by growing cultured rat cortical neurons in microfluidic devices. A fraction of the neurons was stimulated using optogeneti

Having a patient specific mapping of the eloquent cortex is crucial for patients undergoing resective surgery. Non-invasive neuroimaging modalities like magnetoencephalography (MEG) are increasingly used for pre-surgical mapping due to high temporal resolution. Phase-amplitude coupling (PAC), a form of cross-frequency coupling, involves the modulation of high-frequency amplitude by the phase of low-frequency oscillations. PAC observed during tasks reflect interactions between microscale and macroscale neural ensembles. The objective of this study was characterizing whether PAC differs during t