Topic: default EEG reactivity

The default mode network`s (DMN) can be investigated using default EEG reactivity (DER).The default oscillatory macrostate (DEM) is exemplified by the macrostate showing thehighest decrease in occurrence probability during intermittent photic stimulation (IPS).This study aimed to investigate DER, in the deeply sedated epileptic brain.We used a genetic rat model of absence epilepsy, the adult Wistar Albino Glaxo Rijwijk(WAG/Rij) rat. Controls consisted of age-matched Wistar rats.Deep aesthetic coma was induced by chloral hydrate. We performed cortical EEG recordingsduring the induced altered st

Neurological prognosis for comatose patients resuscitated after cardiac arrest remains challenging. Functional imaging suggests that altered connectivity of the brain’s default mode network (DMN) could predict poor outcomes. Unfortunately, functional imaging is not easily applicable at the bedside.We proposed a neurophysiological method that assesses DMN function by computing the default EEG reactivity (DER). The method maps continuous EEG to a sequence of recurring oscillatory patterns termed macrostates. We labelled the default EEG macrostate (DEM) as the macrostate with the lowest probabili