Topic: delta power

Early life stress (ELS) significantly impacts neurodevelopment and behavior. Recent studies suggest a strong link between ELS and poor sleep quality. Poor sleep correlates with increased risk of psychiatric disorders such as anxiety and vulnerability to stress. In this study, we investigated ELS effects on sleep architecture and spindle activity in mice. Two groups were used: ELS group experienced maternal separation for 3 hours daily from postnatal day 1-14, and a stress-naive control group. At the 8 weeks age, EEG and EMG electrodes were implanted for sleep recording. While wake and NREM sle

Rapid eye movement sleep (REM) is often considered as a homogeneous state of sleep, defined by a striking resemblance of its electroencephalogram (EEG) to the one observed in wakefulness. The occurrence of transient events in REM, such as limb twitches or facial and rapid eye movements, supports the view of a paradoxical state of sleep. Here, we investigated the local activity of the primary somatosensory or barrel cortex (S1) in naturally sleeping head-fixed male mice during REM. Through local field potential (LFP) recordings, we uncovered local appearances of spindle waves in the barrel cort