Columbia’s NeuroTechnology Center brings together cellular, systems and computational neuroscientists to examine dendritic computation, cortical circuitry, neuronal cell types and emerging neurotechnologies. The programme connects synaptic physiology and dendritic integration with neuronal morphology, cortical microcircuits, transcriptomics and methods for studying the mammalian brain. Speakers are Peter Jonas, Gábor Tamás, Idan Segev, Henrike Planert, Lida Kanari and Jonathan Ting, with two panel discussions. The online symposium takes place on 10 December 2026, 11:00–16:00 EST (America/New_
Seminar · Computational Neuroscience
Data-driven reduction of dendritic morphologies with preserved dendro-somatic responses
Willem Wybo · Morrison lab, Forschungszentrum Jülich, Germany
Thu, Jun 10, 2021 · 16:30 UTC
There is little consensus on the level of spatial complexity at which dendrites operate. On the one hand, emergent evidence indicates that synapses cluster at micrometer spatial scales. On the other hand, most modelling and network studies ignore dendrites altogether. This dichotomy raises an urgent question: what is the smallest relevant spatial scale for understanding dendritic computation? We have developed a method to construct compartmental models at any level of spatial complexity. Through carefully chosen parameter fits, solvable in the least-squares sense, we obtain accurate reduced co