Topic: Dietary restriction

Age-related declines in sensory, motor, and cognitive abilities are a major risk factor for neurodegenerative diseases. Dietary restriction (DR) can slow or postpone these changes, improving memory, learning, and cognitive abilities, but may not always yield positive results. In this study, we examined the impact of 30% DR (70% of ad libitum daily intake) during adolescence on the short-term (STM) and long-term (LTM) memory performance in 6- and 18-month-old female Wistar rats. The effects of DR were examined in three onsets and durations: DR1 (28th to 35th day of life), DR2 (35th to 42nd day

Dietary restriction (DR), has been shown to improve brain health and function, partly by enhancing GABAergic function and improving the excitation-inhibition balance. However, very few neuro-behavioral studies have explored the beneficial effects of DR outside models of age-related neuropathologies. Therefore, here, we set out to explore DR's-therapeutic potential for stress-induced psychopathologies, by utilizing the "Individual behavioral profiling" approach. Towards that end, after exposing the animals to stress, an “individual Behavioral Profiling” analysis was used to identify, prior to t