Re-analysing the Allen Gene Expression ISH dataset with deep learning
The Allen Gene Expression ISH dataset has been a highly impactful resource for Neuroscientists. Mapping the location within the brain of more than 20,000 genes, it has transformed our understanding of the relationship between gene expression and neuroanatomical structures. Nevertheless, at nearly 20 years old, the accuracy of aligning or matching the ISH section images to the corresponding regions or structures in the atlas was limited by the registration technology available at the time. As a result, the registrations provided by the Allen Institute are accurate to approximately 300 μm. Here