ECoG

…that brain recordings (fMRI, MEG, ECoG) acquired while participants read or listened to unconstrained speech can be predicted by representations extracted from state-of-the-art text- and speech-based LLMs. In particular, text-based LLMs tend to align better with higher-level language regions, capturing more semantic aspects, while speech

Recent studies have revealed an essential contribution of cortical astrocyte calcium activity in regulation of sleep depth and state transitions (Bojarskaite et al., 2020, Nat Comms; Vaidyanathan et al., 2021, Nat Comms). However, astrocytic activity is highly heterogeneous across brain regions, and it is unclear if astrocytes mediate sleep transitions in a brain region specific manner. A region of utmost interest to investigate astrocytic activity during sleep is the hippocampus, which not only display high astrocytic heterogeneity (Viana et al., 2023, Glia), but also shows sleep-specific pat

Neural recordings are often high-dimensional while latent dynamics related to behavior are low-dimensional. Similarly, ethological behaviors are described by large numbers of dynamic features and it is important to know both the dimensionality and composition of the neurally relevant behavioral subspace. However, methods for data-driven identification of behavioral subspaces relevant for neural recordings is nascent. Here, we introduce external Dynamics Components Analysis (eDCA), a linear dimensionality reduction method that finds subspaces of past neural data that have maximal mutual informa

…dye transients (VS), cortical ECoG, and hippocampal LFP in anesthetized mice. Both VS and ECoG show cortical avalanches. When measuring avalanches from the VS

Every day when we fall asleep we lose consciousness, we are not there. And then, every morning, when we wake up, we regain it. What mechanisms give rise to consciousness, and how can we explain consciousness in the realm of the physical world of atoms and matter? For centuries, philosophers and scientists have aimed to crack this mystery. Much progress has been made in the past decades to understand how consciousness is instantiated in the brain, yet critical questions remain: can we develop a consciousness meter? Are computers conscious? What about other animals and babies? We have embarked i