Topic: electroencephalographic recordings

Despite many different medications, 30% of epileptic patients remain drug-resistant, in particular those with mesial-temporal lobe epilepsy (MTLE). MTLE is characterized by focal seizures arising in the temporal lobe, and is associated with hippocampal sclerosis in 80% of patients, as well as with several cognitive and emotional comorbidities. Resection of the epileptogenic zone, although effective, is very invasive, risky and generates side effects. To develop a non-invasive and effective treatment, we evaluated the therapeutic potential of synchrotron-generated X-ray microbeams, an innovativ

Sixty years after the discovery of a slow monotonic drift in electroencephalographic recordings preceding voluntary self-paced actions ("the readiness potential"), its physiological underpinnings remain elusive. A classical interpretation holds that readiness potential onset reflects the decision to act, with the drift thereafter proceeding deterministically to movement onset. However, more recent analyses suggest that the readiness potential's monotonicity may be an artifact of trial averaging; rather than a slow, deterministic process, fast stochastic processes underlie self-paced decisions.