ePoster · Neuroendocrinology
Neuroendocrine dysregulation in microglial cells during the progression of Alzheimer's disease: Preliminary insights from gene expression analysis
Arif Kamil Salihoglu · FENS Forum 2024
OBJECTIVE: Alzheimer's disease (AD) stands as the prevalent neurodegenerative condition globally, characterized by symptoms such as memory loss, language difficulties, disorientation, diminished motivation, self-neglect, mood fluctuations, and behavioral challenges. Despite its widespread impact, the precise cellular mechanisms underlying the onset of AD remain elusive. This study aims to uncover potential pathophysiological contributors to AD by analyzing gene expression levels through bioinformatics approaches. METHODS: GSE129296 dataset downloaded from Gene Expression Omnibus (GEO) database