Epigenetic regulation

…angiogenesis, metabolism, genetic and epigenetic regulation, and tumour immunity. The scientific focus connects mechanisms of cancer initiation, progression and metastasis with the tumour microenvironment and their potential therapeutic implications. Applicants submit their research vision and supporting academic material

…inflammation, metabolism, genetic and epigenetic regulation, and cancer immunology. The research objective is to clarify mechanisms of tumour initiation, progression and metastatic dissemination and connect fundamental findings with therapeutic development. The employer provides a role-specific online applicat

…biology, genome stability, epigenetic regulation, stem cells and the neurobiology of aging. The appointment includes teaching, mentoring, collaborative research and university service. Priority review is 15 November 2026.

This conference examines how chromatin and epigenetic regulation shape gene expression, development and disease. It covers DNA methylation, histone and RNA modifications, non-coding RNAs, heterochromatin, nucleosome structure and nuclear architecture. Researchers will connect transcriptional control with developmental processes and disease mechanisms, using single-cell genomics and advanced microscopy alongside molecular approaches. The programme also considers how ageing, environmental exposures and lifestyle influence epigenetic states. The meeting brings together researchers working across

Recent evidence suggests that epigenetic mechanisms may contribute to memory deficits in aging. Specifically, in the hippocampus, the repressive epigenetic mark H3K9me3 (tri-methylated lysine 9 on histone H3) has been implicated in the silencing of genes essential for memory. Yet, the impact of the age-related increased H3K9me3 levels on neuronal function remains unclear. We hypothesized that H3K9me3 accumulation renders neurons refractory to stimulation. To assess the influence of H3K9me3 on neuronal activation, we reduced H3K9me3 levels by silencing the major methyltransferase responsible to

One of the most prominent features of the human brain is the fabulous size of the cerebral cortex and its intricate folding, both of which emerge during development. Over the last few years, work from my lab has shown that specific cellular and genetic mechanisms play central roles in cortex folding, particularly linked to neural stem and progenitor cells. Key mechanisms include high rates of neurogenesis, high abundance of basal Radial Glia Cells (bRGCs), and neuron migration, all of which are intertwined during development. We have also shown that primary cortical folds follow highly stereot