Topic: experimental design

This course develops a metabolomics investigation from experimental design through data preparation and statistical interpretation. Lectures, practical work and group discussion connect analytical chemistry and data collection with reproducible analysis. Exercises cover R data handling and visualisation, xcms processing of untargeted mass-spectrometry data, quality control, missing values and compound annotation. The final module compares univariate tests, multiple-testing correction, principal-component methods, partial least squares and random forests for metabolomic matrices. Sessions: 16,

Develop optical spectroscopy and plasma diagnostic systems for isotope applications. Research includes experimental design, laser-induced and optical-emission measurements, and analysis of challenging materials in collaboration with the Isotope Applications Research group. Applications are made on the employer’s recruitment portal; no closing date is stated. Initial appointment up to 24 months, with extensions dependent on performance and funding.

Neurofeedback provides a feedback display which is linked with on-going brain activity and thus allows self-regulation of neural activity in specific brain regions associated with certain cognitive functions and is considered a promising tool for clinical interventions. Recent reviews of neurofeedback have stressed the importance of applying the “double-blind” experimental design where critically the patient is unaware of the neurofeedback treatment condition. An important question then becomes; is double-blind even possible? Or are subjects aware of the purposes of the neurofeedback experimen

Consciousness is a phenomenon unlike any other studied in natural science. Yet when building theories and designing experiments, we often proceed as if this were not the case. In this talk, I present two recent investigations of mine which explore the implications of consciousness' unique epistemic context for scientific theory building and experimental design. The first investigation is concerned with falsifications of theories of consciousness and identifies a rather deep problem in the usual scheme of testing theories. The second is an axiomatization and subsequent formalization of some of