Topic: fetal programming

Emerging evidence suggests that intrauterine exposures to maternal factors such as to maternal pre-pregnancy body mass index (MBMI) impacts the neurodevelopment of the offspring in a region-specific way, possibly contributing to future obesity risk of the offspring. Our study investigates the associations between MBMI and neonatal global white matter integrity in 157 infant-mother dyads from FinnBrain Birth Cohort Study (www.finnbrain.fi). Following TBSS (Tract-based Spatial Statistics) skeletonization, associations between MBMI and mean diffusivity values were assessed using a voxel-wise non-

The prevalence of neurodegenerative diseases like Alzheimer’s or Parkinson’s, and mental disorders like depression or anxiety appears higher in patients with gastrointestinal tract diseases like irritable bowel syndrome and inflammatory bowel disease. Conversely, depressed patients have higher rates of gastrointestinal disorders. Moreover, an altered microbiota, called “dysbiosis” has been reported in both neurological and intestinal diseases, which suggests strong interactions between gut microbes and their host. The emergence of the intestinal microbiota as one of major regulators of gut-bra