Topic: food preference

Administration of cannabinoids has been linked to changes in ingestive behaviours in rodents, in the form of hyperphagia or hypophagia. These effects have been attributed to the action of cannabinoid 1 receptors (CB1R) present in both the central nervous system and the digestive tract. While studies have observed that CB1R agonists and antagonist increase and decrease gross food intake respectively, the role of CB1R in other eating behaviours, such as food preference, is largely unknown. In two separate experiments, we tested the effects of stimulation of the CB1R located in two brain regions

The level of dietary protein is expected to be crucial for food preference because of its essential role in maintaining homeostasis. Here, we used Feeding Experimentation Devices (FED3s) to assess food preference and foraging behaviour of protein-restricted vs. control mice. Details are shown in graphical methodology; briefly, adult C57BL/6NRj mice were maintained either on protein-restricted (5% casein: PR) or non-restricted diet (20% casein: NR). Food-preference was tested in four 3-days-apart choice sessions each lasting 24h during which mice were individually placed in a cage with access t

Early-life is a critical window in offspring development. An unhealthy diet during this period can negatively impact offspring metabolic function and eating behaviour later in life​. Microbiota-targeted interventions hold promise for the treatment of aberrant functioning of eating behaviour. This study evaluates the impact of an early-life high-fat/high-sugar (HFHS) diet on eating behaviour later in life, and whether this can be attenuated by microbiota-targeted strategies.Male and female C57BL/6J mice were exposed to either control or HFHS diet from birth for 5 weeks. Afterwards, all mice rec