Topic: forgetting

Many proposed neural circuits for learning are theoretically well-grounded but have limited biological evidence to support them. Emerging anatomical and functional data from neurons in the fruit fly brain allows us to identify interconnections in the mushroom body neuropil that form an 'incentive circuit', supporting rich dynamics of memory acquisition, consolidation and forgetting. In addition, new insights into dopamine function in the fruit fly brain motivate a novel 'dopaminergic plasticity rule' that alters the weights between input sensory patterns and output neurons of the mushroom body

Neural networks need to continuously adapt their representations to survive in a constantly changing environment. To test behavioral flexibility reversal learning paradigms are often used [1]. This flexible adaptation of entrained representations can be mediated by unlearning and forgetting [2]. One possible factor for passive forgetting could be the spontaneous remodeling of neuronal circuitry [3]. Acknowledging that previous studies have presented conflicting views on the effects of forgetting during reversal learning, we hypothesize two potential scenarios: Hypothesis I ('Reusing'): Reusing