Topic: functional calcium imaging

Hearing losses are the most prevalent sensory disorder. The hearing organ, the organ of Corti, is located in a bony capsule in the pars petrosa of the temporal bone. Its spiralling morphology makes it difficult to investigate the cellular mechanism of hearing. The cells provide morphological and physiological differences, called tonotopy, which is the base of the frequency selectivity. The supporting cells have similar variability to the receptor cells, however they receive little attention. One type of the supporting cells are the Deiters cells which are in close connection with the outer hai

Sensory systems relay vital information about changes in the environment to motor command circuits in the brainstem that then select optimal motor actions during navigation. The organization of different sensory inputs and the destination of the integrated output is essential to our understanding of action selection processes. The mechanoreceptive lateral line (LL) system of larval zebrafish (Danio rerio) mediates navigation by detecting flow relative to the body. The LL is innervated by peripheral afferent neurons that project to medial octavolateralis nuclei (MON) in the brainstem. Current m