fUS

…functional ultrasound imaging (fUS) has emerged as a promising technology to fill this gap, enabling neuroimaging investigations of the entire brain in behaving animals. To explore the potential of fUS, and demonstrate its validity against well-established tec

…mice using functional ultrasound (fUS). Unlike traditional fMRI, fUS allows recording brain activity in awake, behaving mice without anesthesia. We established a pipeline for processing fUS data and applied it to behavioral mouse data from a preclinical model of autism carrying a Shank2 gene knockout mutation. The pipeline includes several pre-processing stages, a deconvolution-based method for investigating neuronal activity underlying the fUS signal, and an analysis using hidden Markov models (HMM) to

…protein 43 (FTLD-TDP) and FTLD with Fused in