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Fusiform gyrus

3 ePosters

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fMRI study reveals enhanced top-down and bottom-up processes in schizophrenia

Shuhei Hara, Keita Suzuki, Akio Murakami et al. · COSYNE 2025

In schizophrenia, disrupted perceptual processes are attributed to both hallucinations and delusions in positive symptoms [1, 2]. However, it remains unclear how top-down and bottom-up processes are represented across a visual hierarchy related to distinct symptoms, such as hallucinations, delusions, and negative symptoms. Our goal is to identify the visual areas involved in aberrant top-down and bottom-up processes that contribute to distinct symptoms in schizophrenia. To investigate this, we conducted a functional magnetic resonance imaging (fMRI) experiment with a perceptual decision-making

Neuroscience

Two New Cytoarchitectonic Areas Identified on the Anterior Fusiform Gyrus

Manuel Dietermann, Sebastian Bludau, Hartmut Mohlberg, Katrin Amunts · Bernstein Conference 2024

The fusiform gyrus (FG) in the human brain is essential for higher cortical functions such as recognizing faces and human bodies [1, 2]. Though, the relationship of its structural and functional decompositions in the anterior portion is yet to be better understood [3]. Here, the anterior FG was investigated in ten postmortem brains (five female, five male, including the BigBrain [4]). Using a reproducible, histologically based and software-supported approach, digitized coronal histological brain sections were analyzed [5-7]. A "Grey Level Index" method was used to determine cytoarchitectonic b

Neuroanatomy

Learning a word, involves mapping low-level perceptual representations of world-referents to high-level semantic representations. It is widely held that conscious access to the visual world-referents is needed to learn the meaning of words. The aim of this study was to use fMRI-based decoded neurofeedback (DecNef) to incept a perceptual meaning into brain representations of meaningless symbols, and do so without participant’s awareness, hence by-passing the explicit mapping between words and perceptual referents in brain regions involved in semantic representation. Accordingly, we developed

Cognition