Topic: Gaussian mixture models

Along with other visual features, chromatic information is extracted by the retina. The excitatory, feedforward pathways of chromatic signals in the mouse retina have recently been investigated (Szatko et al., 2020), but it is unclear how inhibitory cell types contribute. In particular, a systematic characterization of chromatic responses in amacrine cells (ACs), the largest and most diverse retinal class of inhibitory neurons, is missing, and the ACs’ role in color processing remains unknown. One challenge in studying AC responses is the fact that most of them lack axons and signal primarily

The Blue Brain Project endeavors to reconstruct and simulate the rodent brain at various scales: from single-neuron gene expression profiles and membrane permeabilities to large-scale neuronal circuits. One important aspect is the biologically accurate morphological structure of neurons, as morphology constrains the connectivity and impacts the functionality of brain networks. Biologically realistic dendrites within brain regions could be successfully synthesized using topological neuron synthesis (TNS), but inter-regional connectivity remains largely an open question which we address in this