Topic: Golgi staining

Schizophrenia is a neuropsychiatric syndrome that affects around 1% of the world population. It is characterized by psychotic or positive symptoms, negative symptoms and cognitive deficits. Currently, antipsychotic treatments can help to manage psychotic symptoms in acute episodes of schizophrenia. However, there is an unmet medical need for the treatment of those cognitive symptoms that appear since the premorbid phase and affect almost 98% of patients. Despite the identification of some molecular pathways that are impaired in schizophrenia, little is known about the possible contribution tha

Vaccinia-related kinase 2 (VRK2) VRK2 is one of the serine/threonine kinases that was originally identified in highly proliferative cells such as thymocytes and fetal liver cells. GWAS studies were reported that VRK2 was related molecule with neuropsychiatric diseases. And in vitro studies reported that VRK2 plays an important role in cell division and cell cycle regulation. However, little is known about the molecular mechanism and physiological function of VRK2 on the central nervous systems in vivo. In this study, we established vrk2 deficient (VRK2 KO) zebrafish and found that VRK2 KO body