Topic: gray matter

The escalating global obesity epidemic underscores the need to understand its intricate health implications. Research highlights associations between elevated body mass index (BMI) and structural changes in both white and gray matter (WM, GM). Given the indirect nature of BMI as an indicator of adiposity, a comprehensive evaluation of body composition becomes essential. This study explores distinct adipose tissue compartments, adipokine levels, and their interplay with structural alterations in both WM and GM, elucidating the complex relationship between obesity, brain structure, and metabolic

Functional Ultrasound imaging (fUS) has recently demonstrated the feasibility of assessing functional connectivity (fC) in neonates at bedside1, facilitating brain monitoring in this vulnerable population. Here, we validate fUS in a larger cohort of preterm neonates to investigate fC in a music exposure paradigm for which MRI studies have shown improved structural and functional maturation2,3. Our study involved n=21 preterm neonates (27.6±2.2 gestational week (GW)) born at Geneva University Hospitals : a control group with standard care (n=10) and a second group repeatedly exposed (2 to 3 tim

Exploring the molecular aspects of the human brain’s structural arrangement can provide insights into its underlying functional mechanisms. The search for differences in white matter regions often focuses on measuring myelin layer thicknesses or parameters of diffusion tensor imaging. Lipids are vital components of cell membranes and are involved in important physiological functions such as signal transmission, maintaining membrane structure, and supporting the development of neurons. This research involved analyzing the distribution of lipids in different areas of the human brain, specificall