Topic: Hemispheric asymmetry

Hemispheric asymmetry in functional connectivity of the orbitofrontal cortex (OFC) has been recently demonstrated in reward-related cognitive tasks like gambling. In this work, which was part of our Neuromatch Academy 2022 project, we used resting state and task-dependent fMRI data from 339 human subjects from the Human Connectome Project (HCP 2020) to quantify the asymmetry of functional connectivity between left and right OFC, and posterior OFC (pOFC) regions during rest and task blocks. We then aimed to relate this asymmetry index (AI) to reward-driven impulsivity traits, quantified by subj