ePoster · Computational Neuroscience
Two opposing forces in inhibitory spike-timing-dependent plasticity differentially regulate network connectivity
Dylan Festa, Claudia Cusseddu, Julijana Gjorgjieva · Bernstein Conference 2024
Inhibitory neurons (I), akin to their excitatory (E) counterparts, adjust synaptic efficacies in response to neural activity. Contrary to the traditional view of inhibition as a purely global activity modulator, recent studies highlighted the importance of specificity in (E/I) wiring and motif structures. These motifs, encompassing mutual and lateral inhibition, take essential functional roles in tuning of receptive fields, learning of representations, predictive coding, and in the regulation of the degrees of freedom of the network’s dynamics (i.e. the network dimensionality). Despite numero