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Topic: information content

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In Chemistry and Computational Neuroscience

Job · Physical Chemistry

Doctoral Researcher in Pulse Electron Paramagnetic Resonance

Deadline not stated

Develop pulse electron-paramagnetic-resonance methods with improved sensitivity and information content. Combine controlled spectrometer experiments with spin-dynamics simulation and applications to inorganic chemistry, catalysis and organic radicals. Optical hyperpolarisation is a further research direction. The SNSF-funded doctorate remains open while advertised until a suitable candidate is found. Apply through the ETH online recruitment portal.

Quantification of information content and its temporal variation in intracellular calcium spike trains in neurons helps one understand functions such as memory, learning, and cognition. Such quantification could also reveal pathological signaling perturbation that potentially leads to devastating neurodegenerative conditions including Parkinson's, Alzheimer's, and Huntington's diseases. Accordingly, the estimation of entropy rate, an information-theoretic measure of information content, assumes primary significance. However, such estimation in the present context is challenging because, while